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SepsisLab

Human-AI Collaboration · Medical Decision-Making · Sepsis Diagnosis

Rethinking human-AI collaboration in complex medical decision making senarios.
Overview

AI decision-support systems often focus on predicting the “right” answer, yet this approach can conflict with how experts actually make complex, high-stakes decisions. Through a case study of sepsis diagnosis, we investigated how clinicians interact with existing AI support and found that final-stage predictions were often perceived as late, opaque, and difficult to act on. We designed SepsisLab, a human-centered AI system that instead supports intermediate stages of clinical reasoning through future risk prediction, uncertainty visualization, actionable lab-test recommendations, and counterfactual exploration. The project proposes a shift from AI as a competing decision-maker toward AI as a collaborator that helps experts explore hypotheses, gather evidence, and reduce uncertainty while preserving human agency over final decisions.

How should AI support human reasoning without taking away human agency?

Institution

Human-Centered AI Lab, NEU

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Timeline

2023 Summer

3 months

 

Role

Literature review

Interview

Interface Design

 

© 2026 by Nomy Jianing Yu.

 

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